CLDN1 Polyklonale Antilichaam
Gecertificeerd

CLDN1 Polyklonale Antilichaam

Catalog #: bs-1428R-01
Maat: 20 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.

Synonyms

AI596271; Claudin-1; Cldn1

Gene ID

12737

Swiss Prot

O88551

Cellular Locus

Cell membrane

Host

• Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

121-211/211

Target

CLDN1

Clonality

• Polyclonal

Isotype

• IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from mouse Claudin 1

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

12737

Beschrijving

CLDN1 Polyklonale Antilichaam Beschikbaar in 20 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamCLDN1 Polyklonale Antilichaam
Categorie
Beschikbare grootte20 µL
Catalogusnummerbs-1428R-01