CLEC4M Antilichaam - N-terminaal gebied: Biotine (ARP42396 T100-Biotine)

C-type lectin domain family 4, member M

CD299, LSIGN, CD209L, L-SIGN, DCSIGNR, HP10347, DC-SIGN2, DC-SIGNR

10332

Q9H2X3

NP_055072

Human, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human CLEC4M

CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

TLR2; MME; CLEC4M; CD209; ICAM3; ITGAM; AP2M1; HCVgp1

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Human: 100%; Pig: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

44kDa

Liu, H., (2006) J. Infect. Dis. 193 (5), 698-702

Wet Ice

399

CLEC4M

CLEC4M

Rabbit

C-type lectin domain family 4 member M

NM_014257

LVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAV