CNTFR Antilichaam

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

1271

P26992

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 41kDa

IgG

CNTFR

Ciliary neurotrophic factor receptor

Homo sapiens

CNTFR, ciliary neurotrophic factor receptor, MGC1774, CNTFR alpha, ciliary neurotrophic factor receptor alpha precursor

WB, IHC

Liquid