CNTNAP1 Antilichaam

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

8506

P78357

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CNTNAP1 (NP_003623.1) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

U-937

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 170kDa

IgG

WB: 1:500 - 1:2000

CNTNAP1

PC-12

Mouse brain

Rat kidney

Contactin associated protein 1

Homo sapiens

CNTNAP1, CASPR, CNTNAP, NRXN4, P190

WB

Liquid