(-) -Codonopsine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(-) -Codonopsine is an alkaloid that can be found in Codonopsis clematidea. It has antibacterial and hypotensive activities. The MIC value of (-) -Codonopsine against Escherichia coli (E. coli) is 64 μg/mL. (-) -Codonopsine is expected to be used in the research of anti-infection and cardiovascular fields[1][2].
26989-20-8
12352005
Bacterial
Anti-infection
COVID-19-immunoregulation
Infection; Cardiovascular Disease
O[C@@H]1[C@H](N([C@@H]([C@H]1O)C)C)C2=CC(OC)=C(C=C2)OC
C14H21NO4
267.32
[1]Iida H, et al. Stereochemical revision and absolute configuration of codonopsinine[J]. Tetrahedron letters, 1986, 27 (44) : 5393-5396.|[2]El-Nezhawy AOH, et al. Design and total synthesis of (-) -codonopsinine, (-) -codonopsine and codonopsinine analogues by O- (2-oxopyrrolidin-5-yl) trichloroacetimidate as amidoalkylating agent with improved antimicrobial activity via solid lipid nanoparticle formulations. Bioorg Med Chem. 2019 Apr 1;27 (7) :1263-1273.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N11554/
Natural Products
No Development Reported
Beschrijving
(-) -Codonopsine is an alkaloid that can be found in Codonopsis clematidea. It has antibacterial and hypotensive activities. The MIC value of (-) -Codonopsine a
Specificaties
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