Cofiline (fosfo Ser3) Antilichaam

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

1072

P23528

NP_005498.1

Human, Mouse, Rat

Cofilin (Phospho-Ser3) antibody was raised against a peptide sequence around phosphorylation site of serine 3 (M-A-S (p) -G-V) derived from Human cofilin.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

19 kDa

This antibody detects endogenous level of cofilin only when phosphorylated at serine 3.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

CFL1

Cofilin 1 (non-muscle)

Homo sapiens

Kobayashi M, et al. (2006) EMBO J 25 (4) : 713-26. Wang Y, et al. (2005) Biol Chem 280 (13) : 12683-9. Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.

CFL, HEL-S-15, HER2, MLN19, NEU, NGL, CFL, CFL1

WB, IHC, IF

5031635

Liquid