Coflin1 / cofilin2 (Ab 88) Antilichaam

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

1072;1073

P23528Q9Y281

NP_005498.1; NP_068733.1

Human, Mouse

Coflin1/cofilin2 (Ab-88) antibody was raised against a peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from Human coflin1/cofilin2.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

19 kDa

This antibody detects endogenous level of total cofilin1/cofilin2 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

CFL1 CFL2

Cofilin 1 (non-muscle) / cofilin 2 (muscle)

Homo sapiens

Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830. Arber, S. et al. (1998) Nature 393, 805-809. Yang, N. et al. (1998) Nature 393, 809-812.

CFL, HEL-S-15, RNF53, Cofilin, non-muscle isoform 18 kDa phosphoprotein

WB, IHC, IF

5031635 / 14719392

Liquid