COG2 Antilichaam - N-terminalgebied: FITC (ARP54815_P050-FITC)

Component of oligomeric golgi complex 2

LDLC, CDG2Q

22796

Q14746

NP_031383

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human COG2

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]) .[supplied by OMIM].

MTUS2; UBC; COG7; COG8; COG3; COG6; COG5; COG1; COG4

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

COG2 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

83kDa

Sohda, M., (2007) Traffic 8 (3), 270-284

Wet Ice

738

COG2

COG2

Rabbit

Conserved oligomeric Golgi complex subunit 2

NM_007357

KRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDKALNQ

2