Coiline (COIL) (NM 004645) Humaan Recombinant eiwit

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies) . Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human coilin (COIL), Met1-Lys220, with N-terminal His tag, expressed in E. coli, 50ug

CLN80; p80-coilin

8161

P38432

NM_004645

17q22

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Stem cell - Pluripotency

24.9 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

COIL

Human

NP_004636

https://www.ncbi.nlm.nih.gov/gene/8161

https://www.uniprot.org/uniprot/P38432

https://www.ncbi.nlm.nih.gov/nuccore/NM_004645

https://www.ncbi.nlm.nih.gov/nuccore/NP_004636