Collageen type II, monoklonale antilichamen (Clone CIIC1)

This antibody binds specifically to the C1 epitope on triple helica collagen type 2. It cross-reacts with mouse, rat, chicken, baboon and horse. Collagen type II, encoded by the COL2A1 gene, is a crucial component of cartilage and plays a vital role in maintaining joint integrity. In mouse models of arthritis, such as collagen-induced arthritis, COL2A1 is studied for its role in cartilage degradation, a key feature of conditions like rheumatoid arthritis and osteoarthritis. Research on COL2A1 helps in understanding arthritis mechanisms and developing new treatments.

This antibody binds specifically to the C1 epitope on triple helica collagen type 2. It cross-reacts with mouse, rat, chicken, baboon and horse. Collagen type II, encoded by the COL2A1 gene, ...

Collagen Type II, Monoclonal Antibody (Clone CIIC1), 100ug

Mouse, Rat, Chicken, Horse, Baboon

Derived from B cells of collagen type 2 immunized DBA/1 mice.

CIIC1

Immunohistochemistry (IHC), ELISA, in vivo functional assays, such as Collagen-Induced Arthritis.

Antibodies

It is recommended that the user determine the optimal dilution for their application. The typical starting working dilutions are IHC 1:100 and ELISA 1:1000.

This antibody is soluble and supplied in PBS.

Human IgG1, k