Collageen XVII/COL17A1 Rabbit mAb (AMR12350N)
Gecertificeerd

Collageen XVII/COL17A1 Rabbit mAb (AMR12350N)

Catalog #: AMR12350N-01
Maat: 50 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Background

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Collagen XVII/COL17A1 Rabbit mAb (AMR12350N) .

Synonyms

BA16H23.2; BP180; BPA-2; BPAG2; ERED; LAD-1

Gene ID

1308

UniProt

Q9UMD9

Cellular Locus

Cell junction, Membrane, Secreted, Single-pass type II membrane protein, basement membrane, extracellular matrix, extracellular space, hemidesmosome

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 130,180kDa Observed MW: 180KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1308

Uniprot URL

https://www.uniprot.org/uniprot/Q9UMD9

AA Sequence

Email for sequence

Beschrijving

Collageen XVII/COL17A1 Rabbit mAb (AMR12350N) Beschikbaar in 50 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamCollageen XVII/COL17A1 Rabbit mAb (AMR12350N)
Categorie
Beschikbare grootte50 µL
CatalogusnummerAMR12350N-01