COLQ Antilichaam - N-terminaal gebied: Biotine (ARP34362_P050-Biotine)

Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

EAD, CMS5

8292

Q9Y215-8

NP_536805

Human, Mouse, Rat, Cow, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human COLQ

COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.

UBC; MUSK; BCHE; ACHE

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Ishigaki, K., et al., (2003) Neuromuscul. Disord. 13 (3), 236-244

Wet Ice

329

COLQ

COLQ

Rabbit

Acetylcholinesterase collagenic tail peptide

NM_080544

LQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLF