COMMD7 Antilichaam

COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1) . It associates with the NF-kB complex and suppresses its transcriptional activity (2) . COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3) . COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4) . COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4) .

149951

Q86VX2

NP_444269

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

COMMD7 antibody is affinity chromatography purified via peptide column.

Cat. No. 1406 - Mouse Spleen Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (95%)

COMMD7 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

COMMD7 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.

COMMD7

Cat. No. 10-901 - Human Spleen Tissue Slide

COMM domain containing 7

Homo sapiens

Maine GN and Burstein E. COMMD proteins and the control of the NF kappa B pathway. Cell Cycle 2007; 6:672-6.

Burstein E, Hoberg JE, Wilkinson AS, et al. COMMD proteins, a novel family of structural and functional homologs of MURR1. J. Biol. Chem. 2005; 280:22222-32.

Narindrasorasak S, Kulkarni P, Deschamps P, et al. Characterization and copper binding properties of human COMMD1 (MURR1) . Biochemistry 2007; 46:3116-28.

Zheng L, Liang P, Li J, et al. ShRNA-targeted COMMD7 suppresses hepatocellular carcinoma growth. PLoS One 2012; 7:e45412.

COMMD7 Antibody: C20orf92, dJ1085F17.3, C20orf92, COMM domain-containing protein 7

ELISA, WB, IHC-P, IF

151101369

Liquid