COMP Antilichaam

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .

1311

P49747

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_000086.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction, Stem Cell

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

COMP

Cartilage oligomeric matrix protein

Homo sapiens

EDM1, EPD1, MED, PSACH, THBS5, TSP5, cartilage oligomeric matrix protein, cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple), pseudoachondroplasia (epiphyseal dysplasia 1, multiple), thrombospondin-5

WB, IHC

Liquid