COMP Antilichaam - N-terminaal gebied: Biotine (ARP41670_P050-Biotine)

Cartilage oligomeric matrix protein

MED, CTS2, EDM1, EPD1, TSP5, PSACH, THBS5

1311

P49747

NP_000086

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the N-terminal region of Human COMP

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .

OTX1; FN1; COL9A1; COL2A1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

83kDa

Wet Ice

757

COMP

COMP

Rabbit

Cartilage oligomeric matrix protein

CVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQV