Complement Factor D/Adipsin Proteïne, Rhesus makak (HEK293, Fc)

Complement Factor D/Adipsin Protein is a member of the S1, or chymotrypsin, family of serine peptidases. Complement Factor D is expressed by adipose cells, plays an important role in both physiology and pathophysiology, where it plays a regulatory role in the complement system. Complement Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Complement Factor D/Adipsin Protein, Rhesus macaque (HEK293, Fc) is the recombinant mouse-derived Complement Factor D/Adipsin protein, expressed by HEK293, with C-hFc labeled tag.

Complement Factor D/Adipsin Protein, Rhesus macaque (HEK293, Fc), Mouse, HEK293

12352202

721138 (Gene_ID) H9EXC1 (Q21-A253) (Accession)

Approximately 53 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

[1]Chen J, et al. Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes. Front Immunol. 2023 Sep 6;14:1225957.|[2]Forneris F, et al. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science. 2010 Dec 24;330 (6012) :1816-20.

Room temperature in continental US; may vary elsewhere.

Recombinant Proteins