Connexine 43 (fosfo Ser265) Antilichaam

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

2697

P17302

NP_000156.1

Human, Mouse, Rat

Connexin 43 (phospho Ser265) antibody was raised against a peptide sequence around phosphorylation site of Serine 265 (Q-K-Y (p) -A-Y) derived from Human Connexin 43.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

43 kDa

IgG

Connexin 43 antibody detects endogenous levels of Connexin 43 only when phosphorylated at Serine 265

Western Blot: 1:500~1:1000

GJA1

Gap junction protein, alpha 1, 43kDa

Homo sapiens

Toshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725.

Toshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519.

Masayuki Shimada, Biol Reprod, Apr 2001; 64: 1255.

Merry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928.

CX43, CXA1, CXN-43, GJA1

WB

4504001

Liquid