COPB1 Antilichaam - middengebied: Biotine (ARP52371_P050-Biotine)

Coatomer protein complex, subunit beta 1

COPB, BARMACS

1315

P53618

NP_057535

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human COPB1

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

SUMO2; NUDCD1; UBC; RNF2; EZH2; KLC1; DIAPH1; ARCN1; ACACA; COPG1; COPZ1; TLE3; FBXO6; UBD; KCNK3; KCNK9; NPM1; HDAC10; ERBB2IP; SNTA1; LZTS2; VPS18; NUB1; SERTAD1; FOXB1; IRAK3; TANK; ID1; HLA-DPB1; GRB2; XRCC6; FN1; CFTR; FMNL1; COPG2; COPE; COPB2; COPA

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

107kDa

Goryachev, A.B. PLoS Comput. Biol. 2 (12), E172 (2006)

Wet Ice

953

COPB1

COPB1

Rabbit

Coatomer subunit beta

NM_016451

QLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCS

Beta