COPS4 Polyklonale Antilichaam, PerCP-Cy5,5 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
CH4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 complex homolog subunit 4; COP9 complex S4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 signalosome complex subunit 4; COP9 signalosome subunit 4; COPS4; CSN complex subunit 4; CSN4; CSN4 SCHPO; CSN4_HUMAN; DCH4; JAB1 containing signalosome subunit 4; JAB1-containing signalosome subunit 4; MGC94896; SGN4; Signalosome subunit 4.
51138
• Rabbit
Human, Mouse, Rat
101-220/406
COPS4
• Polyclonal
• IgG
PerCP-Cy5.5
KLH conjugated synthetic peptide derived from human COPS4
WB, IF (IHC-P)
Purified by Protein A.
482nm/694nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
51138
Beschrijving
COPS4 Polyklonale Antilichaam, PerCP-Cy5,5 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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