COPS8 Antilichaam / COP9 signaalsome complexe subeenheid 8 / CSN8

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. [UniProt]

Western blot: 1:500-1:2000

Q99627

Human

A synthetic peptide from human COP9 signalosome complex subunit 8 protein was used as the immunogen for the COPS8 antibody.

28C83

WB

Affinity chromatography

Purified

This COPS8 antibody is available for research use only.

Store the COPS8 antibody at -20°C.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the COPS8 antibody should be determined by the researcher.

Western blot testing of human HepG2 cell lysate with COPS8 antibody. Predicted molecular weight ~23 kDa and ~18 kDa (two isoforms) .