Corticotropine-releasing factor (schapen)

Corticotropin-releasing factor (CRH) is a peptide hormone involved in stress responses. Corticotropin-releasing factor (CRF) is a major regulatory peptide in the hypothalamic-pituitary-adrenal (HPA) axis under stress conditions. Corticotropin-releasing factor (CRH) can be used for the research of neuroendocrine and anxiety-like behaviors[1][2].

9015-71-8

CRH (Sheep)

12352209

Others

Others

Neuroscience-Neuromodulation

Neurological Disease

99.67

DMSO : ≥ 2 mg/mL

O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

C205H339N59O63S

4670.31

[1]R Zhang, et al. Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice. Mol Psychiatry. 2017 May;22 (5) :733-744. |[2]Kazunori Kageyama, et al. Signal transduction in the hypothalamic corticotropin-releasing factor system and its clinical implications. Stress. 2011 Jul;14 (4) :357-67.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P3538/Corticotropin-releasing-factor-Sheep-SDS-MedChemExpress.pdf

Peptides

Phase 4