COX15 Antilichaam

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region.

1355

Q7KZN9

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human COX15 (NP_510870.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 60kDa

IgG

COX15

A-431

Jurkat

Mouse heart

Mouse kidney

Mouse lung

Cytochrome c oxidase assembly homolog 15 (yeast)

Homo sapiens

COX15, CEMCOX2

WB, IHC, IF

Liquid