COX17 Mouse Monoklonale Antilichaam [Kloon ID: LBI7H5]

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) COX17 mouse monoclonal antibody, clone LBI7H5

MGC104397; MGC117386

Homo sapiens cytochrome c oxidase copper chaperone COX17 (COX17), transcript variant 2, mRNA.

10063

Q14061

Unconjugated

Metabolic pathways, Oxidative phosphorylation

Metabolic pathways, Oxidative phosphorylation

WB 1:2000, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

COX17

https://www.ncbi.nlm.nih.gov/gene/?term=10063

https://www.uniprot.org/uniprot/Q14061