CPDT
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2. The activities of key phase 2 enzymes, including glutathione S-transferase, NAD (P) H:quinone:oxidoreductase 1 and glutamate cysteine synthetase, and levels of glutathione were elevated by CPDT in rat bladder in vivo and in cultured bladder cells in vitro[1][2].
14085-33-7
12352005
H301-H412
Keap1-Nrf2
NF-κB
Neurological Disease
S=C1SSC2=C1CCC2
C6H6S3
174.31
P264-P270-P273-P330-P405-P501
[1]Xiao-Yun Liu, et al. Neuroprotective effect of CPDT on THA-induced cortical motor neuron death in an organotypic culture model. Brain Res Bull. 2010 Nov 20;83 (6) :345-50. |[2]Joseph D Paonessa, et al. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3 (4H) -thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009 Jun 15;180 (1) :119-26.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W975966/
Reference compound1
No Development Reported
Beschrijving
CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2. The activities of key phase 2 enzymes, including glutathione S-t
Specificaties
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