CPI-203-PEG1-C3-O-COOH
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CPI-203-PEG1-C3-O-COOH is a conjugate of the BRD4 ligand and the linker (HY-42427). CPI-203-PEG1-C3-O-COOH can be used for synthesizing PROTAC BRD4 degrader ARV-771 (HY-100972).
1997304-12-7
12352005
Epigenetic Reader Domain; Target Protein Ligand-Linker Conjugates
Epigenetics; PROTAC
Cancer-programmed cell death
Cancer
CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NCCOCCCOCC(O)=O)=O)C3=NN=C(C)N34)=C4S1
C26H30ClN5O5S
560.06
[1]Gao Y, et al. GLUTs-Facilitated Targeting BRD4 Degradation in Breast Cancer through Carbohydrate-Conjugated PROTACs. J Med Chem. 2025 Aug 28;68 (16) :17046-17064.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-42429/
Reference compound2
No Development Reported
Beschrijving
CPI-203-PEG1-C3-O-COOH is a conjugate of the BRD4 ligand and the linker (HY-42427). CPI-203-PEG1-C3-O-COOH can be used for synthesizing PROTAC BRD4 degrader ARV
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