CPI-444
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1, and anti-CTLA-4 induced T-cell-mediated tumor responses, inhibited tumor growth, and enabled antitumor immune memory.1,2 Currently in clinical trials for multiple cancers.3
Unconjugated
Beige solid
-20°C
Beschrijving
CPI-444 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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