CPSF6 Antilichaam - middengebied HRP (ARP40697 T100-HRP)

Cleavage and polyadenylation specific factor 6, 68kDa

CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7

11052

Q16630

NP_008938

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human CPSF6

CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

ARMC7; OTUB2; TOLLIP; PPIL1; FUS; FXR2; WWOX; EZH2; SUZ12; EED; rev; ITCH; PRPF40A; WBP4; TCERG1; NEDD4; APBB1; SRPK2; WWP1; NUDT21; LMNA; CD81; TP63; UBC; NPM1; FN1; DAB2; CSNK2A1; SMURF1; BARD1; MDC1; ZBTB8B; CPSF7; NUP107; TBC1D2; WBP11; PUF60; U2AF2

HRP: Horseradish Peroxidase

Polyclonal Antibody

IF, IHC, WB

CPSF6 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

61kDa

Rual, J.F., (2005) Nature 437 (7062), 1173-1178

Wet Ice

551

CPSF6

CPSF6

Rabbit

Cleavage and polyadenylation specificity factor subunit 6

NM_007007

PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP