CQY684
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CQY684 (PCA062 antibody) is a human monoclonal antibody (mAb) targeting CDH3/P-cadherin. CQY684 stabilizes the X-dimer of P-cadherin, promoting its endocytosis and directing it to lysosomal degradation. CQY684 can be used in Breast, esophageal, and head and neck cancers research[1].
PCA062 antibody
12352203
Cadherin
Cytoskeleton
Cancer-programmed cell death
Cancer
[CQY684]
[1]Tam A, et al. Using genome-wide CRISPR screen to understand resistance mechanisms to PCA062, a P-cadherin targeting antibody-drug conjugate[J]. Cancer Research, 2019, 79 (13_Supplement) : 4743-4743.|[2]Xie B, et al. Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody. Nat Commun. 2025 Jan 29;16 (1) :1157.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991342/
Inhibitory Antibodies
No Development Reported
Beschrijving
CQY684 (PCA062 antibody) is a human monoclonal antibody (mAb) targeting CDH3/P-cadherin. CQY684 stabilizes the X-dimer of P-cadherin, promoting its endocytosis
Specificaties
Recent bekeken producten
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 1 µm
DCFG-L007
1 mL
DiagPoly™ Carboxyl Polystyrene Particles, 1.0 µm
DNM-F029
10 mL
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 0.2 µm
DCFG-L004
1 mL
Optical EtBr filter, 610 nm for SmartView Pro Imager System, 1100 & 2100 series (for UV)
UVCI-1100-EB
1 Unit
AGPAT4 Antibody
MBS7124622-01
0.05 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Recent gezochte producten
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 1 µm
DCFG-L007
1 mL
DiagPoly™ Carboxyl Polystyrene Particles, 1.0 µm
DNM-F029
10 mL
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 0.2 µm
DCFG-L004
1 mL
M-90-422 AF Systems Consumables
131576
Box of 180 Label(s)
Consumable Pack M996030
WAT1096
1 Each
Consumable Pack M996039
WAT1108
1 Each
Consumable Pack M996034
WAT1106
1 Each
Consumable Pack M996038
WAT1102
1 Each