CRBN ligand-190
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CRBN ligand-190 is a is a CRBN-type E3 ubiquitin ligase ligand, can be used for the synthesis of PROTACs, such as PROTAC HPK1 Degrader-7.
1543013-96-2
12352005
Ligands for E3 Ligase
PROTAC
Inflammation/Immunology
FC1=CC(N(C(N2)=O)CCC2=O)=CC=C1
C10H9FN2O2
208.19
[1]Zhang Z, et al. Design, synthesis, and pharmacological evaluation of novel isoindoline-based HPK1 degraders. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118366.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-179730/
Reference compound1
No Development Reported
Cereblon
Beschrijving
CRBN ligand-190 is a is a CRBN-type E3 ubiquitin ligase ligand, can be used for the synthesis of PROTACs, such as PROTAC HPK1 Degrader-7.
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