CRBN ligand-192
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CRBN ligand-192 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC BRD4 Degrader-41. PROTAC BRD4 Degrader-41 is a potent BRD4 PROTAC degrader with anti-cancer activity[1].
12352005
Ligands for E3 Ligase
PROTAC
Cancer
N[C@@H](CCC1=CC=CC=C1)C(NC2CCC(NC2=O)=O)=O
C15H19N3O3
289.33
[1]Huang K, et al. Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands. Eur J Med Chem. 2026 Feb 5;303:118387.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-179735/
Reference compound1
No Development Reported
Cereblon
Beschrijving
CRBN ligand-192 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC BRD4 Degrader-41. PROTAC BRD4 Degrader-41 is a potent BRD4 PROTAC
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