CREB1 Antilichaam - middengebied: HRP (ARP39811 P050-HRP)

CAMP responsive element binding protein 1

CREB, CREB-1

1385

P16220

NP_604391

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human CREB1

CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

CREB1 is strongly supported by BioGPS gene expression data to be expressed in HT1080 There is BioGPS gene expression data showing that CREB1 is expressed in HEK293

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Mamdani, F., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 500-504

Wet Ice

341

CREB1

CREB1

Rabbit

Cyclic AMP-responsive element-binding protein 1

NM_134442

TYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAAREC