CREM Antibody - N-terminal regio : FITC (ARP34777_T100-FITC)

CAMP responsive element modulator

ICER, CREM-2, hCREM-2

1390

O75519

NP_874386

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human CREM

CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

CREB1; PIAS3; CASP8AP2; UBE2I; UBC; SP100; ATXN1; EMP3; HHV8GK18_gp81; MAPK3; CREB3L4; HDAC1; CREB3L1; TAF4; CAMK2D; GSK3A; FHL5; GSK3B; KCNIP3; CAMK2G; PRKACA; CSNK1A1; CREBBP; TBP; PRKCA; SPI1; CREM; ATF1; CDC34; CDK1; CSNK2A2; CSNK2A1; CD34

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

13kDa

Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65

Wet Ice

120

CREM

CREM

Rabbit

CAMP-responsive element modulator

NM_182717

MAAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATRKRELR