Crizanlizumab (anti-P-selectine)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Crizanlizumab (anti-P-selectin) is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1) . Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease[1][2][3].
1690318-25-2
12352203
P-selectin
Immunology/Inflammation
Inflammation/Immunology
[Crizanlizumab(anti-P-selectin)]
[1]Hannah A. Blair, et al. Crizanlizumab: First Approval. Drugs. 80, 79-84 (2020) . |[2]Ataga KI, et al. Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease. N Engl J Med. 2017 Feb 2;376 (5) :429-439.|[3]Ravirajsinh Jadeja, et al. Therapeutic potential of Crizanlizumab (anti-P-selectin) in improving sickle cell retinopathy in mice. Investigative Ophthalmology & Visual Science June 2023, Vol.64, 4747.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P9987A/
Inhibitory Antibodies
No Development Reported
Beschrijving
Crizanlizumab (anti-P-selectin) is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycopro
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