CRKL Antilichaam, KO gevalideerd

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

1399

P46109

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CRKL (NP_005198.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Immunology, Neuroscience, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 37kDa

IgG

CRKL

Jurkat

SKOV3

Mouse brain

Rat heart

V-crk avian sarcoma virus CT10 oncogene homolog-like

Homo sapiens

CRKL, v-crk sarcoma virus CT10 oncogene homolog (avian) -like, v-crk avian sarcoma virus CT10 oncogene homolog-like

WB, IF

Liquid