CRKL Antilichaam - middengebied: FITC (ARP30524 P050-FITC)

1399

P46109

NP_005198

Human

The immunogen is a synthetic peptide directed towards the middle region of Human CRKL

CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.

HUWE1; UBC; BAG3; PIK3R2; DOK1; CBL; LMNA; SHANK3; GAREM; BIK; AOX1; WAC; POLR1D; TENC1; KHDRBS1; PPFIBP2; ARHGEF5; YY1; RPL31; ERBB3; ERBB2; PHC2; BCAR1; RAPGEF1; EPS15; EGFR; ABL1; STAT5A; PIK3R1; EPOR; ELAVL1; MSL1; PLEKHA1; LTBP4; PLSCR1; NOTCH2; LAMA

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

CRKL is strongly supported by BioGPS gene expression data to be expressed in K562

0.5 mg/ml

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Wet Ice

303

CRKL

CRKL

Rabbit

Crk-like protein

NM_005207

RSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPS