CrkRS Antilichaam / CDK12 / Cycline-afhankelijke kinase 12
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CrkRS, also known as Cdc2-related kinase, arginine/serine-rich, CDK12 and Cyclin-dependent kinase 12, is a cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. It also regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability.
Western blot: 1:500-1:1000
Q9NYV4
• Rabbit
Human, Mouse
A portion of amino acids 1-30 from the human protein was used as the immunogen for this CrkRS antibody.
• Polyclonal
• Ig
WB
Purified
This CrkRS antibody is available for research use only.
Aliquot the CrkRS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
In 1X PBS, pH 7.4, with 0.09% sodium azide
Titration of the CrkRS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Western blot testing of mouse liver tissue lysate with CrkRS antibody. Predicted molecular weight ~164 kDa.
Beschrijving
CrkRS, also known as Cdc2-related kinase, arginine/serine-rich, CDK12 and Cyclin-dependent kinase 12, is a cyclin-dependent kinase that phosphorylates the C-ter
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