CRMP-2 (fosfo Thr509) Antilichaam

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

1808

Q16555

NP_001377.1

Human, Mouse, Rat

CRMP-2 (phospho Thr509) antibody was raised against a peptide sequence around phosphorylation site of threonine 509 (S-V-T (p) -P-K) derived from Human CRMP-2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

50 kDa

IgG

The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

DPYSL2

Dihydropyrimidinase-like 2

Homo sapiens

Miki Y., Science 266:66-71 (1994) .

Smith T.M., Genome Res. 6:1029-1049 (1996) .

Wilson C.A., Oncogene 14:1-16 (1997) .

CRMP2, N2A3, TOAD-64, DPYL2, ULIP2

WB, IHC

3122051

Liquid