CRSP8 (MED27) Mouse Monoclonal Antibody [Kloon ID: LBI2A4]

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

Carrier-free (BSA/glycerol-free) MED27 mouse monoclonal antibody, clone LBI2A4

CRAP34; CRSP8; CRSP34; MED3; NEDSCAC; TRAP37

Homo sapiens mediator complex subunit 27 (MED27), transcript variant 1, mRNA.

9442

Q6P2C8

Unconjugated

WB 1:500~2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MED27

https://www.ncbi.nlm.nih.gov/gene/?term=9442

https://www.uniprot.org/uniprot/Q6P2C8