CRTC2 Antilichaam / TORC2

CRTC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. [UniProt]

Western blot: 1:500-1:2000

Q53ET0

Human

A synthetic peptide from human CREB-regulated transcription coactivator 2 protein was used as the immunogen for the CRTC2 antibody.

28C77

WB

Affinity chromatography

Purified

This CRTC2 antibody is available for research use only.

Store the CRTC2 antibody at -20°C.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the CRTC2 antibody should be determined by the researcher.

Western blot testing of human 293T cell lysate with CRTC2 antibody. Predicted molecular weight ~73 kDa.