CRY1 Antilichaam

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

1407

Q16526

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human CRY1 (NP_004066.1) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

Mouse testis

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

WB: 1:500 - 1:2000

CRY1

Mouse eye

Rat testis

SW480

Cryptochrome circadian clock 1

Homo sapiens

CRY1, Chryptochrome 1, Cryptochrome-1, Photolyase homolog 1, PHLL1

WB

Liquid