CRY1 Antilichaam

Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL

12952

Q16526

NP_031797.1

Mouse

CRY1 antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

This antibody detects endogenous level of total CRY1 protein.

Western Blot: 1:500~1:1000

Cry1

Cryptochrome 1 (photolyase-like)

This antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.

Morioka N, et al. (2010) J Pharmacol Sci. 113 (3) : 234-45. Fonseca F, et al. (2010) Mol Diagn Ther. 14 (3) : 171-8. Stratmann M, et al. (2010) Genes Dev. 24 (12) : 1317-28.

Phll1, AU020726, AU021000, PHLL1

WB

6681031

Liquid