CRYGC Antilichaam - middelste regio: FITC (ARP52388_P050-FITC)

Crystallin, gamma C

CCL, CRYG3, CTRCT2

1420

P07315

NP_066269

Human, Rat, Cow, Dog, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human CRYGC

Crystallins are the dominant structural components of the vertebrate eye lens.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MIP; HSPB2; HSPB1; CRYGD; CRYGC; CRYBB2; CRYAB; CRYAA

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

CRYGC is supported by BioGPS gene expression data to be expressed in OVCAR3

0.5 mg/ml

Cow: 79%; Dog: 93%; Horse: 86%; Human: 100%; Rabbit: 86%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Leung, T., (er) Mol. Vis. 13, 1333-1338 (2007)

Wet Ice

174

CRYGC

CRYGC

Rabbit

Gamma-crystallin C

NM_020989

GLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE