Cryptochrome I (CRY1) Mouse Monoclonal Antibody [Kloon ID: LBI6C6]

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]

Carrier-free (BSA/glycerol-free) CRY1 mouse monoclonal antibody, clone LBI6C6

PHLL1

Homo sapiens cryptochrome circadian regulator 1 (CRY1), mRNA.

1407

Q16526

Unconjugated

Circadian rhythm - mammal

Circadian rhythm - mammal

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CRY1

https://www.ncbi.nlm.nih.gov/gene/?term=1407

https://www.uniprot.org/uniprot/Q16526