CRYZ-antilichaam

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.

1429

Q08257

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human CRYZ (NP_001123514.1) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience, Signal Transduction

Affinity purification

K-562

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 37kDa

IgG

WB: 1:500 - 1:2000

CRYZ

Mouse liver

Mouse brain

Mouse kidney

Rat kidney

Crystallin, zeta (quinone reductase)

Homo sapiens

CRYZ, DKFZp779E0834, FLJ41475

WB

Liquid