CSL-360
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CSL-360 is a chimeric unconjugated IgG1 monoclonal antibody targeting CD123. CSL-360 efficiently prevents the binding of IL-3 to CD123, abolishing IL-3 induced cell proliferation. CSL-360 can be used for acute myeloid leukemia (AML) research[1][2].
12352100
Interleukin Related
Immunology/Inflammation
Cancer
[1]Slade MJ, et al. CD123 bi-specific antibodies in development in AML: What do we know so far? Best Pract Res Clin Haematol. 2020 Dec;33 (4) :101219.|[2]Chichili GR, et al. A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates. Sci Transl Med. 2015 May 27;7 (289) :289ra82.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991648/
Inhibitory Antibodies
No Development Reported
IL-13
Beschrijving
CSL-360 is a chimeric unconjugated IgG1 monoclonal antibody targeting CD123. CSL-360 efficiently prevents the binding of IL-3 to CD123, abolishing IL-3 induced
Specificaties
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