CtBP1 (fosfo Ser422) Antilichaam

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

1487

Q13363

NP_001319.1

Human, Mouse, Rat

CtBP1 (phospho Ser422) antibody was raised against a peptide sequence around phosphorylation site of Serine 422 (A-P-S (p) -P-G) derived from Human CtBP1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

48 kDa

IgG

The antibody detects endogenous levels of CtBP1 only when phosphorylated at serine 422.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

CTBP1

C-terminal binding protein 1

Homo sapiens

Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471 (1995) .

Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787 (1999) .

The MGC Project Team, Genome Res. 14:2121-2127 (2004) .

CTBP, C-terminal binding protein 1, EC 1.1.1

WB, IHC

4557497

Liquid