CTCFL Antilichaam - N-terminaal gebied: Biotine (ARP36128_P050-Biotine)

CCCTC-binding factor (zinc finger protein) -like

CT27, BORIS, CTCF-T, HMGB1L1, dJ579F20.2

140690

Q8NI51

NP_542185

Human

The immunogen is a synthetic peptide directed towards the N terminal region of human CTCFL

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SP1; BAG6; HIST2H2AC; HIST1H1A; PRMT7; HIST1H3A; BRCA1

Biotin

Polyclonal Antibody

WB

Affinity Purified

CTCFL is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Sun, L., (2008) Cancer Res. 68 (8), 2726-2735

Wet Ice

663

CTCFL

CTCFL

Rabbit

Transcriptional repressor CTCFL

NM_080618

CREKDHRSPSELEAERTSGAFQDSVLEEEVELVLAPSEESEKYILTLQTV