CTDSP2 Antilichaam - middengebied: FITC (ARP52097_P050-FITC)

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

OS4, PSR2, SCP2

10106

O14595

NP_005721

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human CTDSP2

CTDSP2 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.CTDSP2 negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. CTDSP2 is recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.CTDSP2 may contribute to the development of sarcomas.

CDCA3; UBC; AR; SNAI1; POLR2A

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

CTDSP2 is strongly supported by BioGPS gene expression data to be expressed in RPMI-8226

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 91%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Wet Ice

271

CTDSP2

CTDSP2

Rabbit

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

NM_005730

ASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRA