CTLA4-eiwit (C-His, mens)

CTLA4

ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12

C-His

< 0.05 EU per mg protein.

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS (Routinely tested) .

1.Loaded Anti-CTLA4 (Research Grade Ipilimumab Biosimilar) on ProA Biosensor, can bind Recombinant Human CTLA4 / CD152 Protein (His Tag) (Cat. No. 11159-H08H-UE) with an affinity constant of 14.6 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Ipilimumab-Derived Anti-CTLA4 Antibody, Human IgG1 captured on Protein A chip, can bind Recombinant Human CTLA4 / CD152 Protein (His Tag) (Cat: 11159-H08H-UE) with an affinity constant of 21.600 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

Lys36-Phe162

The recombinant human CTLA4 consists of 138 amino acids and has a predicted molecular mass of 15 kDa. As a result of glycosylation, the apparent molecular mass of human CTLA4 is approximately 22-27 kDa in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 19.5 kDa verified by SEC-MALS (Routinely tested) .

Human