CTLA4-eiwit (C-human IgG1-Fc, muis)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CTLA4
Cd152, Ctla-4, Ctla4, Ly-56
• HEK 293
C-human IgG1-Fc
< 1.0 EU per μg of the protein as determined by the LAL method
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
1.Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.05-0.3μg/mL when stimulated with 1 μg/mL Recombinant Human B7-1/CD80. 2.Immobilized Recombinant Mouse CD86 / B7-2 Protein (His Tag) (Cat: 50068-M08H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse CTLA4 / CD152 Protein (ECD, Fc Tag) (Cat: 50503-M02H), the EC50 is 2.0-7.0 ng/mL.
Met1-Phe162
The secreted recombinant mouse CTLA4/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 368 amino acids and has a predicted molecular mass of 41 kDa. As a result of glycosylation, the apparent molecular mass of rm CTLA4/Fc monomer is approximately 53 kDa in SDS-PAGE under reducing conditions.
Mouse
Beschrijving
CTLA4-eiwit (C-human IgG1-Fc, muis) Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
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